2007-2008 Fellowship Training Courses in Clinical Oncology

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Basic Training Course (Clinical Oncology)

Radiobiology & Cancer Science Course 2008

Date: 2 August 2008– 6 December 2008
Time: Lecture: 9:00 a.m.– 11:30 a.m. (Sat)
  Workshop: 11:45 a.m. – 1:00 p.m.  
Venue: Lecture:

Conference Room (Room 1203), 12/F, Block R,
Department of Clinical Oncology, QEH

  
  Workshop: 13/F, Block R, Radiobiology & Cancer Research Unit,
Department of Clinical Oncology, QEH		  
Course Fee: HK$ 600 for HKCR trainee
HK$ 1,000 for non-HKCR trainee

Cancer Science Lectures

 

Date
Session

Time

Topic
1. 2/8/08 Lecture

9:00-11:30

General principles of tumour biology & aberrant cell growth control:

  • Definitions of growth disorders, dysplasia and CIS
  • Mechanisms of local invasion & metastasis
  • Basic on cell cycle
  • Control of cell growth
  • Autocrine, paracrine & endocrine growth factors
  • Altered expression in malignancy
2. 9/8/08 Lecture

9:00-11:30

Causation of human cancers:

  • Environmental factors
  • Carcinogenesis
  • Viral carcinogenesis (HPV, EBV etc)
  • Radiation carcinogenesis
    1. Ionising & non-ionising radiation
    2. DNA damage & repair, nucleotide excision repair
    3. Repair genes & gene products
3. 16/8/08 Lecture

9:00-11:30

The genetics of normal and malignant cells:

  • Point mutations, translocations, deletions, gene amplification
  • and over-expression
  • Oncogenes, proto-oncogenes, TS genes (with examples)
  • DNA repair mechanisms
  • Point mutations, translocations, deletions
  • Polymorphism, mini & microsatellites
  • Brief chromatin & chromosomal structure
  • Gene therapy
4. 23/8/08 Lecture

9:00-11:30

Techniques in molecular biology:

  • Nucleic acid analyses including electrophoresis,
  • hybridisation, blotting, PCR, sequencing, transfection
  • Microarray techniques
  • Transgenic models

A. 23/8/08 Workshop

11:45-13:00

Molecular biological techniques for cancer studies (I)
5. 30/8/08 Lecture

9:00-11:30

The epigenetics of normal and malignant cells:

  • DNA hypermethylation, hypomethylation & association with cancer
  • Methylation reversal 
  • Histone acetylation & deacetylation & association with cancer
  • Protein-protein interactions
B. 30/8/08 Workshop

11:45-13:00

Molecular biological techniques for cancer studies (II)
6. 6/9/08 Lecture

9:00-11:30

Growth of normal and malignant cells:

  • Tumor kinetics
  • Signal transduction (MAP kinase pathway etc), kinase inhibitors & cancer
  • Cyclin, cyclin kinases & inhibitors & cancer
  • Gene promoters
7. 13/9/08 Lecture

9:00-11:30

Cancer susceptibility & inheritance genetics:

  • Inherited syndromes: AT, XP, Nijmegin break syndrome
  • Li-Fr, Lynch, MEN, Cockayne, FPC, inherited breast cancer syndromes
  • Genes conferring susceptibility to cancer
  • Familial linkage analysis
  • Genetic counseling
8. 20/9/08 Lecture

9:00-11:30

The physiology of haemopoiesis:

  • Marrow structure and organisation
  • The haemopoietic microenvironment
  • Cell lineages and hierarchies
  • Control mechanisms in normal haemopoiesis
  • Tumour vasculature and angiogenesis
9. 27/9/08 Lecture

9:00-11:30

The immune system:

  • Cellular immune system
  • Antigen recognition & processing
  • Dendritic cells
  • Immunological surveillance
  • Tumor immunology
  • Immuntherapy
C. 27/9/08 Workshop

11:45-13:00

Immunological techniques for cancer studies

Radiobiology Lectures

 

Date
Session

Time

Topic
1. 4/10/08 Lecture

9:00-11:30

General principles of radiobiology:

  • Cellular systems (hierarchical, flexible) and their response to radiation
  • Parallel and linear systems
  • LET and its relevance to cellular damage
  • Radiation damage at the cellular level (membrane, cytoplasmic, nuclear)
2. 11/10/08 Lecture

9:00-11:30

Assays for cell survival & radiation damage:

  • Radiation biology models (monolayer, spheroids, animal)
  • (normal and transgenic), regrowth curves, clonogenic assay, MTT
  • In vitro, in vivo & in situ methods for cell survival & damage determination
  • Acute radiation syndromes & biological dosimetry techniques (dicentric chromosomes & micronuclei etc.)
D. 11/10/08 Workshop 11:45-13:00

Cell culture & mouse models in radiobiology study
3. 18/10/08 Lecture

9:00-11:30

Cell survival curves, radiation damage & repair:

  • Current formulae applied to cell survival curves determination (e.g. Linear quadratic model, α & β cell kill, α/β)
  • Cell cycle sensitivity to radiation, repair of sublethal & potentially lethal damages by radiation (i.e. SLDR & PLDR)
E. 18/10/08 Workshop 11:45-13:00

Biological dosimetry techniques
4. 25/10/08 Lecture

9:00-11:30

Oxygen effects, hypoxia & biological modifiers:

  • Oxygen effects, hypoxia & its model
  • Radiosensitizers, halogenated pyrimidines; radioprotectors
5. 1/11/08 Lecture

9:00-11:30

Physical factors affecting cell survival, fractionation & 4R:

  • Relative biological effectiveness (RBE)
  • RBE & LET, dose, dose rate and fractionation
  • Hyperfractionation and accelerated treatment
  • Repair, reoxygenation, redistribution, repopulation)
6. 8/11/08 Lecture

9:00-11:30

Factors affecting therapeutic ratio & hyperthermia:

  • Influence on therapeutic ratio by dose, dose-rate &, RT fraction numbers
  • Isoeffect curves, NSD system, quality of irradiation
  • Biologically effective dose (BED)
7.

15/11/08
&

22/11/08		 Lecture

9:00-11:30

Tumor and normal tissue radiobiology:

  • Normal tissue damage (early & late)
  • Concept of normal tissue tolerance
  • Factors influencing tolerance
  • Effects of radiation on different tissues & organs
  • Organ tolerance to retreatment with radiation
  • Scheme for reporting normal tissue damage
  • Effects on embryo & foetus
  • Parenchymal & stromal injury
8.

29/11/08
&
6/12/08

Lecture

9:00-11:30

Additional lectures or revision (optional)

 

Medical Physics Course

Date: 14 July 2007 - 23 February 2008
Venue: Room 1203, Block R, Queen Elizabeth Hospital
Course Fee: HK$600 for HKCR trainee
HK$1,000 for non-HKCR trainee

 

Date

Time

Topic

Lecturer
1. 14/7/07

9:00-11:00

 Basic Physics relevant to Radiotherapy John Lam
2. 21/7/07

9:00-10:30

 Electromagnetic Radiation and its interaction with Matter John Lam

10:30-12:00

 Interaction of Sub-Atomic Particles with Matter John Lam
3. 28/7/07

9:00-11:00

 Teletherapy Beam Physics (X-ray)-1 Joel Cheung
4. 4/8/07

9:00-11:00

 Teletherapy Beam Physics (X-ray)-2 Joel Cheung
5. 11/8/07

9:00-11:00

 Radiation Dosimetry-1 Monica Kan
6. 18/8/07

9:00-11:00

 Radiation Dosimetry-2 Monica Kan
7. 25/8/07

9:00-11:00

 Radiation Dosimetry-3 Monica Kan
8. 1/9/07

9:00-11:30

 Beam Therapy Equipment-1 Ricky Chau
9. 22/9/07

9:00-11:30

 Beam Therapy Equipment-2 Ricky Chau
10. 29/9/07

9:00-11:30

 Beam Therapy Equipment-3 Ricky Chau
11. 6/10/07

9:00-11:00

 Radiotherapy Treatment Planning-1 Michael Lee
12. 13/10/07

9:00-11:00

 Radiotherapy Treatment Planning-2 Michael Lee
13. 20/10/07

9:00-11:00

 Radiotherapy Treatment Planning-3 Michael Lee
14. 3/11/07

9:00-11:00

 Radiotherapy Treatment Planning-4 Michael Lee
15. 10/11/07

9:00-11:00

 Radiotherapy Treatment Planning-5 Michael Lee
16. 17/11/07

9:00-11:00

 Radiotherapy Treatment Planning-6 Michael Lee
17. 24/11/07

9:00-11:00

 Radioactive Sources-1 Collin Lui
18. 1/12/07

9:00-11:00

 Radioactive Sources-2 Collin Lui
19. 8/12/07

9:00-11:00

 Brachytherapy-1 Victy Wong
20. 15/12/07

9:00-11:00

 Brachytherapy-2 Victy Wong
21. 22/12/07

9:00-11:00

 Unsealed Sources Joyce Leung
22. 29/12/07

9:00-11:00

 Radiation Protection-1 PM Wu
23. 5/1/08

9:00-11:00

 Radiation Protection-2 PM Wu
24. 12/1/08

9:00-11:00

 Radiation Protection-3 PM Wu
25. 19/1/08

9:00-11:00

 Electron Beam Physics KY Cheung
26. 26/1/08

9:00-11:00

 Quality Assurance KY Cheung
27. 2/2/08

9:00-11:00

 Tutorials-1 Francis Tang
28. 16/2/08

9:00-11:00

 Tutorials-2 Francis Tang
29. 23/2/08

9:00-11:00

 Tutorials-3 Francis Tang

Medical Statistics Course

Date: 6 October 2007 ¡V 2 February 2008
Time: 11:30am ¡V 1:00pm
Venue: Room 1203, Block R, Queen Elizabeth Hospital
Course Fee: HK$400 for HKCR trainee
HK$600 for non-HKCR trainee

 

Date

Topic

Speaker
1. 6/10/07 Summarizing and Presentation of Data PM Wu
2. 13/10/07 Sampling PM Wu
3. 20/10/07 Statistical tests and Significance I PM Wu
4. 03/11/07 Statistical tests and Significance II PM Wu
5. 10/11/07 Statistical tests and Significance III PM Wu
6. 17/11/07 Clinical Trials I (Design, and randomization, sample size calculation) FY Cheung
7. 24/11/07 Clinical Trials II (Protocol, Ethical consent, measure of response) KH Au
8. 01/12/07 Clinical Trials III (Interim analysis Intent to treat & Metaanalysis) KH Au
9. 08/12/07 Epidemiology I Shelly Tse
10. 15/12/07 Survival analysis I TS Choy
11. 22/12/07 Survival analysis II TS Choy
12. 29/12/07 Epidemiology II FY Cheung / Oscar Man
13. 2/2/08 Revision SK Au

Clinical Pharmacology Course 2008
Date: 26 April 2008 – 26 July 2008
Time:
First Lecture: 9:00 am - 10:00am (60 minutes)
 
Second Lecture: 10:00am - 11:00pm (60 minutes)
Venue: Lecture Room, Department of Clinical Oncology, Basement, Li Ka Shing Specialist Clinic (North Wing), Prince of Wales Hospital
Course Fee: HK$ 400 for HKCR trainee
HK$ 600 for non-HKCR trainee

 

Date

Topic

Speaker
1. 26 April 2008 Mode of Action of Cytotoxic Drugs Dr. Pun Hui (PWH)
    Drug Design and Development Prof. Brigette Ma (PWH)
2. 3 May 2008 Endocrine Therapy, Biological & Novel therapies Dr. WM Ho (PWH)
    Principles of Clinical Use Dr. Kenny Lei (PWH)
3. 24 May 2008 Toxicity of Chemotherapy Prof. Winnie Yeo (PWH)
4. 26 July 2008 Pharmacokinetics and Pharmacodynamics Prof. Tony Mok (PWH)
    Clinical Pharmacology of Analgesics & Drug Interactions Dr. SH Yau (PWH)

 

Intermediate Training Course (Clinical Oncology) 2008
Date: 5th January - 4th October 2008 (21 Saturdays)
Time:
First Lecture: 9:00 am - 10:30am (90 minutes)
 
Second Lecture: 11:00am - 12:30pm (90 minutes)
Venue: Lecture Theatre, 12/F, Block R, Dept of Clinical Oncology, R Block, Queen Elizabeth Hospital
Course Fee: HK$ 2,000 for HKCR trainee
HK$ 3,000 for non-HKCR trainee

 

Date

Topic

Speaker / Institute
1. 5th Jan 2008 Experience sharing with successful candidates Successful candidates
Communication Skills / Breaking Bad News QMH / Dr. Rico Liu
2. 26th Jan 2008 Cervix and uterine corpus cancer / Gyn Brachy TMH / Dr. CS Wong
    Thyroid Dr. SM Chow
3. 2nd Feb 2008 Ovary, fallopian tube & peritoneal cancer QEH / Dr. KH Wong
    Anus, vagina and vulva TMH / Dr. KK Yuen
4 16th Feb 2008 Head and Neck (I) - Salivary glands, Ear and paranasal sinus PWH  / Dr. KH Yu
    Esophagus QMH / Dr. Rico Liu
5. 1st Mar 2008 Plasma cell malignancies QEH / Dr. HC Cheng
6. 15th Mar 2008 Radiotherapy (I) - Basic Physics, techniques, radiation safety and Q.A. QMH / Dr. Sherry Ng
7. 29th Mar 2008 Head and Neck (II)- NPC PYNEH / Dr. Anne Lee
    CNS QEH / Dr. YT Fu
8. 26th Apr 2008 Radiotherapy (II) ¡V Planning techniques and plan evaluation PMH / Dr. SH Lee
    Kidney and bladder PWH / Dr. KM Lee
9.

10th May 2008

(venue changed to Room 1203, Block R, QEH)

Head and Neck (III) ¡V Larynx, OP, HP, tongue TMH / Dr. KK Yuen
10. 17th May 2008 Oncologiacl emergencies, supportive and palliative care PYNEH / Dr. Inda Soong
    Germ cell tumour QEH / Dr. VC Sin
11. 24th May 2008 Early Breast Cancer PMH / Dr. Carol Kwok
    RT for benign diseases, special RT techniques QEH / Dr. Angus Leung
12. 14th June 2008 Paediatric Tumour QMH / Dr. Dora Kwong
13. 21st June 2008 Colon and rectum PMH / Dr. KT Yuen
    Liver, pancreas and biliary tract PWH / Dr. LC Chan
14. 5th July 2008 Bone and soft tissue tumour PWH / Dr. WK Tsang
    Other Endocrine tumours e.g. pituitary and carcinoid tumours PYNEH / Dr. R. Yeung
15. 12th July 2008 Pathology QEH / Dr John Chan
    Pathology QEH / Dr John Chan
16. 19th July 2008 Lung QEH / Dr. KC Kwan
    Advanced Breast Cancer QEH / Dr. J Ng
17. 26th July 2008 Prostate / CA penis QMH / Dr. Philip Kwong
    Melanoma PWH / Dr. J Suen
18. 2nd Aug 2008 Skin cancer, ocular and adnexal tumours QEH / Dr. FY Cheung
NHL - extra-nodal sites QMH / Dr. MY Luk
19. 16th Aug 2008 NHL - nodal (1) QEH / Dr. HY Yiu
NHL - nodal (2) QEH / Dr. HY Yiu
20. 30th Aug 2008 Slides review Dr. DTM Chan
    Hodgkin's disease PMH / Dr. M Tong
21. 4th Oct 2008 Mock Viva All 6 centres

Application forms can be downloaded below. For further information please email to our secretariat.
Please send completed registration form and cheque for registration fee to the Secretariat of the College.

Intermediate Training Course 2008 Registration Form (For HKCR Trainee)

Intermediate Training Course 2008 Registration Form (For non-HKCR Trainee)

Basic Training Course in Clinical Pharmacology 2008 Registration Form (For HKCR trainee)

Basic Training Course in Clinical Pharmacology 2008 Registration Form (For non-HKCR trainee)
Basic Training Course in Radiobiology & Cancer Science 2008 Registration Form (For HKCR trainee)

Basic Training Course in Radiobiology & Cancer Science 2008 Registration Form (For non-HKCR trainee)

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